http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1083223-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e3113097dd6d28720572e47f2f2407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b52ab46311bc15853c850b665c8d3c6 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 1999-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ae5e0bd68e527adcae6358007535913 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e53cd5f36f5112e1432790ed7efa0bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01d3c2ad01227ad809d60c5fddae0d07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6e6db81ec6f3c541e84c29c9d773b4b |
| publicationDate | 2006-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1083223-B1 |
| titleOfInvention | Novel immortalized hepatic cell line originating in humans |
| abstract | The present invention relates to a new immortalized hepatocyte culture of human (preferably human fetal) normal cell origin, a method of producing said culture, a screening method for a compound or a salt thereof which inhibits or promotes an enzyme activity involved in the metabolism of xenobiotics in the liver, or which inhibits or promotes the expression of a gene encoding an enzyme involved in the metabolism of xenobiotics in the liver, or which inhibits or promotes the induction of expression of a gene encoding an enzyme involved in the metabolism of xenobiotics in the liver, characterized by the use of said culture, a compound which inhibits or promotes an enzyme activity involved in the metabolism of xenobiotics in the liver, a compound which inhibits or promotes the expression of a gene encoding an enzyme involved in the metabolism of xenobiotics in the liver, or a compound which inhibits or promotes the induction of expression of a gene encoding an enzyme involved in the metabolism of xenobiotics in the liver, obtained using said screening method, or salts thereof. The immortalized hepatocyte culture of human normal cell origin of the present invention is useful in, for example, screening for compounds or salts thereof having therapeutic/preventive effects on hepatic insufficiency . |
| priorityDate | 1998-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 471.