http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1082329-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34fadf00cbf436daf378c00070f76020 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-282 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 1999-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfb39fd535c27cecc6a9eca79f0052c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64b1dff43debad95cd2e91d49a0c201b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c76b69b73ee8c039f4ae430eecc10fd1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff11b090c002cd6df506c71fb662dfa8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_165cd6eaf45759607f9e27435a2c3397 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccf1da6a6bae8858141c91b57c62d440 |
| publicationDate | 2001-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1082329-A1 |
| titleOfInvention | Platinum complex, its preparation and therapeutic application |
| abstract | Disclosed is a platinum complex of formula (I) wherein X represents a halogen atom and A represents a primary tricyclic amine containing 10 to 14 carbon atoms which may be optionally substituted on the tricyclic ring by one or two alkyl group(s) containing 1 to 4 carbon atoms, and, furthermore, an inclusion complex of the above platinum complex with beta- or gamma-cyclodextrin which may be optionally substituted by a hydroxyalkyl group of 1 to 6 carbon atoms. There are also disclosed a method for the preparation of the complex of formula (I) based on bringing into reaction a solution of an alkaline metal salt of ammin-trihalogenplatinate(II) in a polar organic solvent or in water with corresponding tricyclic amine at the temperature in the range of 0 to 100 °C, as well as a method for manufacture of the above inclusion complex. The both disclosed complexes may be used as such or as a part of a pharmaceutical composition in a therapy of oncologic diseases. |
| priorityDate | 1998-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.