http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1082290-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3f4526fdbf9d019c69c6ba524b81a50 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-42 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-42 |
filingDate | 1999-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2003-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b3a5c27c8b81b0cbc97a41098e39b5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63c748d45539d486ea957413a1827cbd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_696d5e460546b88ccbcd4c8c79a35482 |
publicationDate | 2003-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1082290-B1 |
titleOfInvention | Process for the preparation of aceclofenac |
abstract | Compounds of formula (I), wherein R<1>, R<2> and R<3> are independently selected from lower alkyl groups C1-C4 or hydrogen, are particularly useful intermediates in producing Aceclofenac. The compounds are prepared by reacting Diclofenac acid with triethylamine, diisopropylamine or ammonia in a solvent at a temperature of from 20 DEG C to 60 DEG C. The compounds of formula (I) are reacted with an appropriate alpha -haloacetic acid ester to form acetates which are deprotected to form Aceclofenac. Other alpha -Arylpropanoic Acid NSAID's may be prepared analogously. |
priorityDate | 1998-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.