Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc408585f6863d7865c90ab9a4632135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3c2e77f8dfda692ca527454d23ecc03 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
1999-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01555da790bef21aba160bb659f7aa07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2e8e4c58b983d6e49edd62704dcf2ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78cd6a2c33b8a7f0502439394a48426d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5c3f1ce02d53be27105965a118a78a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b37c7cccf96a169f0d2f6cccd622fe33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10160cc840eeb5f2114b9c2ac2b58922 |
publicationDate |
2001-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1079844-A1 |
titleOfInvention |
Chaperone suppression of ataxin-1 aggregation and altered subcellular proteasome localization imply protein misfolding in sca1 |
abstract |
The present invention provides a novel method for treating neurodegenerative disease in mammals. This method involves the introduction of a therapeutic effective amount of a chaperone, a chaperone-like-compound or a compound which increases proteasome activity into the neurological system of the mammal. There is also a novel method for screening for compounds having chaperone-like activity or having activity to increase proteasome activity. The screening works in either cultured cells or animal models. |
priorityDate |
1998-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |