| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6459
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21069 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-48 |
| filingDate |
2000-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee51f718a6de4512fa9e67883ee0c857
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_980a302a0d15d298deba958bc0ac18c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f341caefeb0128f0d50337bcf1123901
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59febe3297e5df41bed07644b777b705 |
| publicationDate |
2001-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1077262-A1 |
| titleOfInvention |
Process for the production of naturally folded and secreted proteins by co-secretion of molecular shaperones |
| abstract |
A process for the production of a naturally folded eukaryotic polypeptide containing two or several cysteines linked by disulfide bridges by a) culturing prokaryotic cells in which the said prokaryotic cells contain an expression vector which codes for the said polypeptide which contains a prokaryotic signal sequence at the N-terminus, b) secreting the polypeptide into the periplasm or the medium, c) cleaving the signal sequence and isolating the polypeptide from the periplasm or the medium, which is characterized in that a nucleic acid coding for a molecular chaperone is additionally expressed in the said prokaryotic cell and the chaperone is secreted into the periplasm, is suitable for the recombinant production of polypeptides in prokaryotes in a high yield. <IMAGE> |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03025116-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03025116-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7244575-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6962982-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03000877-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100702373-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100441755-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7094884-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7094757-B2 |
| priorityDate |
1999-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |