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filingDate 2000-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c1dc53ffee2ec90c47ae02c595373b6
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publicationDate 2001-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1077072-A2
titleOfInvention In vitro process for the preparation of heart valve or vessel prothese
abstract The invention relates to an in vitro method for producing homologous heart valves and vessels.n n n So far, patients suffering from heart valve dysfunction have either been mechanicalnHeart valve or a biological valve from a human ornimplanted non-human donors. However, these flaps have significantnDisadvantages such as the need for lifelong anticoagulation with thenRisk of hemorrhagic complications, a tendency to degeneration and thenRisk of an immune reaction. In addition, none of the previously known flapsne.g. adapt by changing hearts. Comparablenbig problems arise when using vial homografts and plastic vesselsnas a blood vessel replacement.n n n With the method according to the invention, homologous heart valves and blood vessels can be made available which or their wall are made up of an essentially connective tissue core and a superficial endothelial cell layer and thus have a structure analogous to the natural heart valve or the natural vessel. The disadvantages of the known heart valve and vascular prostheses are avoided by the heart valve and blood vessel prostheses according to the invention.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005107642-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2431666-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2130905-A1
priorityDate 1999-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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