http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1074552-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e7022e391363a3cf3486bf3859ce0a7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 |
| filingDate | 2000-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61c509b04b26510c8fba950207420006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf1427e7386a8edb8db57ffdbc6b3861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf5843bfb3cb423491bb8331485a646d |
| publicationDate | 2001-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1074552-A3 |
| titleOfInvention | Process for the preparation of a highly pure phenothiazine compound |
| abstract | According to the method of the present invention, an alkalinmetal compound, dimethyl sulfoxide, trimethyloxosulfonium halidenand 3-quinuclidinone are added in a specific order to give thenfollowing compound [II]. This compound is, without treatment ornisolation, directly reacted with an alkali metal salt ofnphenothiazine to give the following compound [III], from which thenfollowing compound [I] is obtained. During the production ofncompound [I], a by-produced acidic gas is removed and water isnadded to ensure industrial, safe and efficient production ofncompound [I] at a constantly high yield. Inasmuch as the presentninvention enables production of the following highly pure compoundn[A] by eliminating hydrogen halide of compound [I] in glyme in thenpresence of at least one kind of a base selected from potassiumnhydroxide and potassium alkoxide, compound [A] having a highnpurity of not less than 85 mol% can be provided. |
| priorityDate | 1999-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.