abstract |
Described herein is the process for the preparation of 3-substituted 4-phenyl-piperidinenderivatives of formula (I)n nin which X is selected from H and F, and R is selected from the group consisting ofnH, C1-C6 alkyl, C3-C6 alkenyl, and benzyl, comprising three steps starting fromnthe monoamide of malonic acid and cinnamic aldehyde, or derivatives thereof. |