http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1072681-B9
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f6b50e46d46b1e4e352b62b40dd12f6 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
filingDate | 2000-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2003-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5422a11d5b11b7e5b63694e4b766615 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5e30373245f3ef7335f897d257c0f00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1e113f1556daa6d918ba758d6b2af69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba1fb79a09a637aa731e3fe3bdc55acd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acf08abaf9aaad140978a9b710660e22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7465cf965abbe6875b164f05ea1a712b |
publicationDate | 2003-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1072681-B9 |
titleOfInvention | Human-keratinocytes regulator protein pKe#165 |
abstract | An isolated polypeptide (I) comprising: (1) a 354 amino acid (aa) sequence (S2) fully defined in the specification; or (2) an allele or derivative of S2 formed by aa substitution, deletion, insertion or inversion; is able to modify proliferation, adhesion, migration, morphogenesis and/or differentiation of cells, is new. An isolated human epidermal keratinocyte polypeptide (I) comprising: (1) a 354 amino acid (aa) sequence (S2) fully defined in the specification; or (2) an allele or derivative of S2 formed by aa substitution, deletion, insertion or inversion; is able to modify proliferation, adhesion, migration, morphogenesis and/or differentiation of cell and is highly expressed when such cells are in the activated state (as indicated by increased expression of urokinase plasminogen activator and its receptor). Independent claims are also included for the following: (1) a nucleic acid (II) that encodes (I) comprising a 1483 base pair (bp) sequence (S1) fully defined in the specification or its complements, fragments or sequences that hybridize to them; (2) an isolated polypeptide (Ia) derived from a splice variant of mRNA from (II); (3) recombinant DNA (IIa) containing (II) and able to express (I) in prokaryotic or eukaryotic cells; (4) transformed host cells (III) that contain (II), linked to a promoter, present in the cell naturally or as a result of recombination and able to express (I); (5) antibodies (Ab) that react specifically with (I); and (6) a reagent for indirect detection of (I), prepared using at least one of (II) and/or (I). |
priorityDate | 1999-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 347.