| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce5256bc9919dfe0fc41de42b12f1d3a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-75 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-585
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-891
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K6-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-695
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N55-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-55 |
| filingDate |
1999-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd13c99ad6ebec8efb1d5de8dd7ce7e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_944bc58e972d43f6d34da7178a21a0f6 |
| publicationDate |
2001-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1071431-A1 |
| titleOfInvention |
Novel delivery of hydroxy carboxylic acids |
| abstract |
The present invention provides greater than 99 % pure bis(triorganosilyl)hydroxycarboxylates of the general formulae: R3SiO-CHR1-COO-SiR¿3? and R3SiO-CHR?1-R2¿COO-SiR¿3? wherein each R is independently a monovalent straight or branched chain alkyl or alkenyl group having from 1 to about 6 carbon atoms, or an aryl group, R?1¿ may be hydrogen, a monovalent straight or branched chain alkyl group having from 1 to about 18 carbon atoms, or an aryl group, and R2 is a divalent straight or branched chain alkyl group having from 1 to about 18 carbon atoms, an aryl group, or a straight or branched chain alkaryl group having from 7 to about 18 carbon atoms; a process for producing the bis(trimethylsilyl)-hydroxycarboxylates comprising the trimethylsilylation with hexamethyldisilazane of the corresponding hydroxy carboxylic acids; cosmetic formulation comprising the greater than 99 % pure bis(trimethylsilyl)hydroxycarboxylates dissolved in aprotic media; and a method of delivering hydroxycarbxylic acids to the epidermis without apparent irritation or inflammation of the epidermis or stratum corneum. |
| priorityDate |
1998-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |