| abstract |
The present invention relates to subtilisin protease conjugates comprising a protease moiety and one or more addition moieties wherein the protease moiety has a modified amino acid sequence of a parent amino acid sequence, the parent amino acid sequence comprising a first epitope region, a second epitope region, and a third epitope region, wherein the modified amino acid sequence comprises a substitution by a substituting amino acid at one or more positions in one or more of the epitope regions and wherein each addition moiety is covalently attached to one of the substituting moieties. The present invention further relates to cleaning and personal care compositions comprising such protease conjugates. |