| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c211647b8606d863cb35fdf0cb30fba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56aaa02f68d3bd4442cb587d7af1aa08 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-027 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
1999-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2dc482eebdd3b7001d131c760fff436
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20408b30930e3c8a4379cd471d8b795d |
| publicationDate |
2000-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1060246-A2 |
| titleOfInvention |
Method for selecting ribozymes which are capable of covalently modifying the ribonucleic acids on 2'-oh-groups in trans |
| abstract |
The invention relates to an in vitro selection method for selecting ribozymes which are capable of covalently modifying the ribonucleic acids on 2'-OH-groups in trans and to the ribozymes obtained using this method. The invention also relates to medicaments containing said ribozymes, said medicaments being preferably used for inhibiting gene expression - for example in gene therapy. The inventive ribozymes can also be used for producing muteins and nuclease-resistant ribonucleic acids, for example ribonuclease-resistant "antisense" oligonucleotides. |
| priorityDate |
1998-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |