| abstract |
A process for producing a substance KF-1040A represented by formula (I), andnanother substance KF-1040B represented by formula (II), which comprises culturingnmicroorganisms capable of producing the substances KF-1040A and KF-1040B, thusnaccumulating these KF-1040A and/or KF-1040B in the liquid culture and harvesting the samenfrom the culture. Because of the activities of inhibiting diacyloglycerol transferase andnsphingomyelinase, the above substances are useful in preventing and treating arteriosclerosis,nobesity, thrombus, inflammation and immune function-related diseases. |