| abstract |
The invention relates to a combination preparation containing an estrogen and an anti-estrogen, characterized in that the estrogen is chosen from the group consisting of 17- beta -estradiol, 17- alpha -ethinyl estradiol, estriol, estrone, estrone sulfate, estrogen sulfamate, 17- alpha -estradiol, mestranol, stilbestrol and natural conjugated estrogens, and in that the anti-estrogen is a substituted 7 alpha -( xi -aminoalkyl)-estratriene of the general formula (I). The combination preparation provided for in the invention can be used for hormone replacement therapy. |