| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1860f461da678a5c923361823e4eb4e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-00 |
| filingDate |
1999-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db45a5df91a22bff8d2c302519ccbb45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a82c579ca5a2e5e0410fef17197ef3da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_348a949878de0bd68d7af9046627a110
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dc0978a4fce4189007044f9a5960005 |
| publicationDate |
2003-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1053244-B1 |
| titleOfInvention |
Glycosidation of 4,5-epoxymorphinan-6-ols |
| abstract |
Glycosidation of 4,5-Epoxymorphinan-6-ols with a Thioglycoside as a glycoside donor is disclosed. The process comprises reacting a 4,5-Epoxymorphinan-6-ol and a Thioglycoside in the presence of a thiophilic promoter under conditions capable of forming 4,5-Epoxymorphinan-6-glycosides. This novel approach was used for preparation of pharmaceutically important 4,5-Epoxymorphinan-6-beta-D-glucuronides. The process provides both high stereo-selectivity and high yields. |
| priorityDate |
1998-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |