http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1049933-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-581 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D219-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 |
filingDate | 1999-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6923e50c0e6b5d777cb8ca450db9d2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_888c6fd441e4e97f405d325d6a5831e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d961f9da746f31c9911f814ba3ec6968 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_264f8a1c6d9fba00b8d62a21063aa8f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_832705bd4d407fb5bcde9163d90e0c6c |
publicationDate | 2000-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1049933-A1 |
titleOfInvention | Measurement of hydride using chemiluminescent acridinium compounds |
abstract | The present invention discloses a method for the measurement of hydride using a chemiluminescent compound, such as an acridinium compound. The source of hydride for the reduction of acridinium compound may be of chemical or biochemical origin, or the result of enzymatic catalysis. The chemical source of hydride, might be NaBH4. A biochemical source of hydride might be that derived from NADH, or NADPH, while an enzymatic source would be the class of oxidoreductases termed dehydrogenases which convert NADH or NADPH from NAD or NADP. Among applications for acridinium compounds as chemiluminescent indicators of hydride are diagnostic assays using dehydrogenases as reagents, indicators, diagnostic markers or as labels. Ethanol, for example, might be detected with acridinium ester chemiluminescence through the reaction of alcohol dehydrogenase on ethanol, said reaction producing NADH. As a label, dehydrogenase might be used in an ELISA for the detection of a specific analyte with acridinium ester providing the signaling response. |
priorityDate | 1998-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 343.