| abstract |
The present invention relates to methods and intermediates for preparing compoundsnof the formula 1 n n and the pharmaceutically acceptable salts and solvates thereof, as well as structurallynrelated compounds, wherein R 1 , R 2 and R 15 are as defined herein. The foregoing compoundsnare useful in the treatment of hyperproliferative disorders, such as cancers, in mammals. n The present invention also relates to a method of preparing compoundsnof the formula 9 n n and the pharmaceutically acceptable salts and solvatesnthereof, wherein R 6 -R 10 and R 15 are asndefined herein. |