| abstract |
Compounds represented by the general formula (1):n n[wherein R 1 is typically an aminoalkyl group; R 2 is typicallyna hydrogen atom, a lower alkyl group, R 3 or SR 4 (where R 4 isntypically a lower alkyl group); Ar is typically a 5-memberednaromatic heterocyclic group] have an NOS inhibiting activitynand are useful as therapeutics of cerebrovascular diseasesnand other pharmaceuticals. |