http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1034797-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec5b8c0fc1f827c1360a8f5ea5652225 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0491 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-02 |
filingDate | 2000-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2004-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c234369b7b76fd3973e7cb2993adbcb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddf42b007bcf00a83cfdc369cabb5beb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57b4b8033b952abff7aeddc76c300295 |
publicationDate | 2004-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1034797-B1 |
titleOfInvention | Process for the manufacture of an 18F-labelled glycosylation reagent as well as 18F-glycosylation reagent and its use |
abstract | An <18>F-labelled glycosylating agent is prepared by: (a) reaction of a hexose (I) with phosphoric acid (H3PO4); (b) hydrolysis of the product with a base; and (c) reaction of the product with uridine triphosphate (UTP) in the presence of pyrophosphorylase and Mg<2+>. Preparation of an <18>F-labelled glycosylating agent comprises: (a) reaction of a hexose of formula (I) with phosphoric acid (H3PO4); (b) hydrolysis of the product with a base; and (c) reaction of the product with uridine triphosphate (UTP) in the presence of a phosphorylase and Mg<2+>. one group R = <18>F in position 2, 3, 4 or 6 of the hexose ring, and the other three = a protecting group which is linked to the hexose ring via an oxygen atom An Independent claim is included for a glycosylating reagent of formula (II): one group R' = <18>F in position 2, 3, 4 or 6 of the hexose ring, and the other three R' groups = OH; OUDP = a uridine diphosphate group |
priorityDate | 1999-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 164.