| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49310188df8dc04b3708491df863459f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8213
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-90 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 |
| filingDate |
1998-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85060c4f0637c94d23424598671c9501
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86b9538a4d6a38cb216d19a6f40a17f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac3fe4d5ce472a6791b9d1173906cdfa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_532a2ae6ff584ffbd1687072ae460bca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45f4da5366aa8012fcfae3bb8d82a164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8e72078d01ad20bf53960b34c8c8fd5 |
| publicationDate |
2000-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1032680-A1 |
| titleOfInvention |
A novel method for the integration of foreign dna into eukaryoticgenomes |
| abstract |
Compositions and methods for introducing a DNA of interest into a genomic target site are provided. In particular, the methods and compositions involve the use of a combination of target sites for two site specific recombinases and expression of a chimeric recombinase with dual target site specificity. Thus, the compositions comprise novel site-specific recombinases with specificities to multiple target sites, and nucleotide sequences and expression cassettes encoding these recombinases or target sites. The methods involve transforming a eukaryotic cell having target sites for the novel recombinase with a DNA of interest that is flanked by corresponding target sites. Expression of the recombinase results in integration of the DNA of interest into the genome of the cell. The compositions and methods of the invention have use in the construction of stably transformed eukaryotic cells, and in particular, plant cells. The methods result in the efficient targeted genomic integration of DNA by site-specific recombination. |
| priorityDate |
1997-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |