abstract |
The present invention relates to the process for preparing a compound of the formulan n wherein A is C 1 -C 6 alkyl, an aryl which is mono or disubstituted with F, Cl , Br,, OCH 3 ,nC 1 -C 3 alkyl or benzy. In the preferred compound A is CH 3 . The 5-lipoxygenase inhibitors thatnare prepared in accordance with the present invention are selective inhibitors of the action ofnlipoxygenase enzyme and are useful in the treatment or alleviation of inflammatory diseases,nallergy and cardiovascular diseases in mammals. |