http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1023045-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be0b97e5d8024b2588a3e4989231ba0b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 |
filingDate | 1998-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de46b2f9eaa555e17ff47ecd00734444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1d20d4503b84d96ce792e03455e7be0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e31aca4be8f2ee063ae5c96a25ab7c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38786fbf5604a2b5ddb79ab5731b2b33 |
publicationDate | 2000-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1023045-A2 |
titleOfInvention | Delivery vehicles for bioactive agents and uses thereof |
abstract | Compositions for transporting a bioactive agent across a biological membrane include the bioactive agent, an oil, an oil-immiscible compound and a noncationic surface active agent. The compositions may deliver the bioactive agent through a chemical microporulation mechanism, which allows transfer of the agent across both cellular, intracellular organelle, and nuclear membranes. Compositions for nucleic acid delivery include nucleic acid, oil, oil-immiscible compound, noncationic surface active agent and essentially no cationic lipid, or include nucleic acid, oil, oil-immiscible compound and two noncationic surface active agents. The nucleic acid may be hydrophobically-modified, and be in combination with an oil, an oil-immiscible compound and at least one surface active agent. The compositions may be used for gene delivery to a cell, as well as delivery of other therapeutic agent. |
priorityDate | 1997-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 969.