| abstract |
The present invention relates to a method for amplifying the response from a protein expressed from a recombinant vaccinia vector. The present invention may be used to amplify the intended effect of expressed proteins in any method where such expression is desired, for example, in vaccine production, vaccination and gene therapy. The present invention also relates to synthetic peptides, nucleic acid sequences, preferably DNA sequences and constructs comprising a vector linked to a DNA segment which encodes a protein containing a signal peptide at its N-terminus and an anchor sequence at its C-terminus. These expression vectors are generally useful for expressing polypeptides in a variety of animal cells. |