| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7dfd84f9157ae12c41e319ec325338d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
| filingDate |
1998-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58685cf43e423c8703a307596c8ff4f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7520b4324c4b711164daf24ed4838b6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b14c7f70300bf1af941e036ae6af248
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8237a615bdf2e6ccf5e1248b745ac518
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b4c6240818cfd4ba651dcf12d52bdb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_071438774441774905e5de55196244f0 |
| publicationDate |
2000-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1016665-A1 |
| titleOfInvention |
Process for the selective preparation of z-isomers of 3-(2-substituted vinyl)cephalosporins |
| abstract |
Z-Isomers of compounds of general formula (IV): [wherein R 1 is 2-(2-N-protected aminothiazol-4-yl)-2-alkoxyiminoacetyl or the like,nR 1 is hydrogen or the like; R 3 is hydrogen, a carboxyl-protecting group or the like; and R 1 is alkyl or the like] can be prepared at highnselectivities and in high yields by reacting a compound of general formula (I): [wherein R 1 , R 2 and R 3 are each as defined above; and R 4 isnaryl or the like] with a 4-substituted or -unsubstituted thiazole-5-carbaldehyde in a mixed solvent comprising a chlorinated hydrocarbon andna lower alkanol at a temperature of as low as +5 °C or below. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7459550-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005100367-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005003141-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005003141-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005100369-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005016936-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005016936-A3 |
| priorityDate |
1997-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |