| abstract |
The use of substances capable of preventing the binding of a receptor binding form ofnu-PA to a u-PA receptor (u-PAR) in a mammal and thereby preventing u-PA from convertingnplasminogen into plasmin thereby preventing cell surface plasminogen activationnwhich is believed to play an important role in tissue remodelling, particularly during cancerninvasion for preparing a composition for preventing or counteracting localized proteolyticnactivity in a mammal, in particular a human. |