| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82b460ae2c0d553a2db7abd984e85631 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2985
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-839 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1611
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1694
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-27 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 |
| filingDate |
1993-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffdfb79340a0f16f176530c2029e3252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8113cd6025687a5e3b3e63779a1e21bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_258b1d0aec933a64527a4d4845c09761 |
| publicationDate |
2000-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1013270-A2 |
| titleOfInvention |
Controlled release growth hormone containing microspheres |
| abstract |
Growth hormone polymeric controlled release systems are described wherein thengrowth hormone retains good biological activity and is released over an extendednperiod of time following administration by injection. In the preferred embodiment,nhuman growth hormone polymeric microspheres are made using very coldntemperatures to freeze the polymer-growth hormone mixtures into polymericnmicrospheres with very high retention of biological activity and material.nSustained release of biologically active growth hormone is achieved when thenmicrospheres are tested in vivo , extending over a period of greater than one daynto several months. Altered release can be achieved by inclusion of degradationnmodifiers, pore forming agents, and stabilizers of the growth hormone. |
| priorityDate |
1992-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |