http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1012268-A4
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_473f3c3915a09fbebc6395a85d4c3509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7eb539fe69bbc45ed4f392e24c6eae1 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 |
filingDate | 1998-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_985b77228c85e43d20acb719ef5cc760 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94fc5ffa9be223c67d66d2d852e22705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66630be8498c603f46352976f57743d5 |
publicationDate | 2001-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1012268-A4 |
titleOfInvention | IRES SEQUENCES WITH HIGH TRANSLATION EFFICIENCY AND EXPRESSION VECTORS CONTAINING THEM |
abstract | An isolated and cloned translation control element, and analogues thereof, having the nucleotide sequence as set forth in SEQ ID NO:7 and designated SP163, are disclosed. The translation control element controls cap-independent mRNA translation via an internal ribosome entry site (IRES). The present invention provides expression vectors comprising the translation control element SP163 or its analogues operatively linked to a gene sequence to be expressed. In alternative embodiments, the expression vector comprises at least two nucleic acid sequences to be translated and SP163 is operatively linked to at least one of the sequences to be translated. The sequences to be translated may be linked to only one promoter in an embodiment. The present invention further provides a method for facilitating and enhancing cap-independent translation of mRNA by including in an expression cassette a translation control element having the nucleotide sequence as set forth in SEQ ID NO:7 and designated SP163. |
priorityDate | 1997-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 165.