| abstract |
A method of simulating congestive heart failure uses catheters (aortic, right atrial, and left atrial), hydraulic occluders (#1, #2), and pacemaker probes (RV, LA) attached to an animal's heart (not numbered) to simulate a chronic condition. A pressure gauge (LV) and flow probe sensor (aortic) are also attached to the heart to monitor the effects of a test compound on the animal's cardiac function and systemic vascular dynamics. A method for assessing the effects of this test compound is included. |