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filingDate 1998-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa08c28192b148cb9cb13755e7c3b581
publicationDate 2004-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1005573-A4
titleOfInvention DENDRITIC NUCLEIC ACIDS WITH MAXIMUM SELF-ASSEMBLY CAPACITY
abstract Disclosed are nucleic acid matrices comprising a dendrimeric network of interconnected monomers. Each monomeric unit is synthesized using nucleic acid sequences having no repeats of subsequences of a predetermined length. In preferred embodiments, the subsequences have a length of 3-5 nucleotides. The DNA monomers assembled therefrom exhibit maximal self-assembly properties in that they hybridize substantially only to portions of other monomers having complementary sequences. The monomers in the dendrimeric assembly may be cross-linked to enhance structural integrity of the matrix.
priorityDate 1997-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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