abstract |
The present invention relates to compounds, pharmaceutical compositions and methods of using compounds of formula II in the treatment and/or prevention of certain diseases or conditions. <CHEM> In formula II A is chosen from ortho substituted aryl or heteroaryl species, Z is chosen from -OH, -SH, NHR and R<1> is chosen from -(CH2)nL wherein L may be selected from a variety of substituents including aryl, heteroaryl and heterocyclic groups. The compounds are useful in treating and/or preventing neurological disorders associated with excitatory amino acids. |