abstract |
A process for preparing biodegradable microparticles comprising a biodegradablenpolymeric binder and a biologically active agent. A first phase, comprising thenactive agent and the polymer, and a second phase are pumped through a staticnmixer into a quench liquid to form microparticles containing the active agent.nPreferably, a blend of at least two substantially non-toxic solvents, free ofnhalogenated hydrocarbons, is used to dissolve or disperse the agent and dissolve thenpolymer. |