http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0996616-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1860f461da678a5c923361823e4eb4e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-40 |
| filingDate | 1998-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_370d095929e82e6c55f21e83d6382e46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cc3ece0621f92a4177bcf1252f576b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65885a28035cbde1f973cbaab70d91aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a10f0b2a7479d08f05113604f3bab4af |
| publicationDate | 2000-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0996616-A1 |
| titleOfInvention | Process and a novel intermediate for the preparation of flecainide |
| abstract | The present invention provides a process for the preparation of a compound of formula (A) wherein R is a 2-piperidyl or 2-pyridyl radical, and pharmaceutically acceptable salts thereof, which process comprises the steps of: a) reacting 2,5 bis (2,2,2,-trifluoroethoxy) benzoic acid or a salt thereof, with a haloacetonitrile of the formula XCH2CN, where X is C1, Br or I, if necessary in the presence of an inorganic or organic base, to form the cyanomethyl ester of formula (II); b) reacting the ester of formula (II) with an amine of the formula RCH2NH2, where R is as defined above and, if desired; c) converting the compound of the formula (A) to a pharmaceutically acceptable salt thereof. |
| priorityDate | 1997-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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