| abstract |
The present invention relates to new compounds, which asnspecific inhibitors of the cysteine protease dipeptidyl peptidasenI (DP I) act. These connections are through thenrepresents general formula A-B-NHO-Bz, in which A is an N-terminalnunprotected amino acid except proline and hydroxyprolinenwhich is in peptide bond with B, B is anIs amino acid other than proline, hydroxyproline or alanine andnNHO represents a hydroxylamine moiety that bonds in amidenwith B and in ester bond with Bz, Bznis a benzoyl residue which is unsubstituted or in ortho-, meta-nand / or para position is substituted. |