Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28ebf72900689b5f377d0d7b80db96b2 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-495 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
filingDate |
1999-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca00818e68e7138a7237e14988812142 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cba4d182e3827e0e215780c6e82b2d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_322c332e47c6ee2170c4301223caf67c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d16491c0255be818137eaba244bf1c72 |
publicationDate |
2000-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0992586-A2 |
titleOfInvention |
Extracellular matrix proteins with modified amino acid |
abstract |
Incorporation of certain amino acid analogs into polypeptides produced byncells which do not ordinarily provide polypeptides containing such amino acid analogs isnaccomplished by subjecting the cells to growth media containing such amino acidnanalogs. The degree of incorporation can be regulated by adjusting the concentration ofnamino acid analogs in the media and/or by adjusting osmolality of the media. Suchnincorporation allows the chemical and physical characteristics of polypeptides to benaltered and studied. In addition, nucleic acid and corresponding proteins including andomain from a physiologically active peptide and a domain from an extracellular matrixnprotein which is capable of providing a self-aggregate are provided. Human extracellularnmatrix proteins capable of providing a self-aggregate collagen are provided which arenproduced by prokaryotic cells. Preferred codon usage is employed to producenextracellular matrix proteins in prokaryotics. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1149111-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016237117-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03035692-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7122635-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10562956-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7491691-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2876165-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11384117-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7390885-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7566449-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1149111-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7566770-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7588760-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03035692-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9133236-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7763247-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7763248-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10202419-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010004004-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8025883-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012156276-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7345151-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7365167-B2 |
priorityDate |
1998-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |