| abstract |
The invention discloses an ultrasound contrast media comprising a microbubble shell and a composition of general formula: A-P-L, wherein A is an ultrasound contrast agent microbubble-shell binding moiety; P is a spacer arm; and L is a ligand. The present invention discloses compositions, methods of imaging, and methods for attachment of targeting ligands to USCM agents, allowing selective targeting of USCM agents to desired sites. |