http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0986401-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d43c883aa035c2b0560e1968520554fd |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 1998-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_766cfc7e2847fed7ef077d76c5f2c4bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13215cad1db02d28e0769e0b0d062015 |
| publicationDate | 2000-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0986401-A1 |
| titleOfInvention | P-selectin translocation to vascular epithelial lumen by ionizing radiation |
| abstract | The present invention relates to the use of P-selectin as a targeting agent in radiotherapies for vascular related disease. P-selectin is translocated to the lume of vascular endothelia as a result of radiation. Thus, P-selecting provides a target for receptor-mediated delivery of drugs, including anticancer drugs and drugs for the treatment of vascular disease. However, P-selectin also plays a role in the activation of certain inflammatory cells and, as such, plays a role in radiation-induced inflammation. By interfering with P-selectin induction of inflammation, it is possible to modulate inflammatory responses to radiation therapy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016534057-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10596387-B2 |
| priorityDate | 1997-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1614.