| abstract |
This patent application describes the use of molecularnimprinting as a means for preparation of anti-idiotypicnimprint matrices. With this technique, imprints ofnartificial or natural molecules including their recognitionnsites, such as of molecularly imprinted polymers ornbiological receptors, antibodies or enzymes, can be prepared.nIn the former case, using the original imprints asncasts or molds in a subsequent polymerisation step, utilisingnpreferentially functionally complementary monomers,nthe formation of imprint materials containing recognitionnsites complementary in shape and functionality with thenoriginal imprint can be obtained but being of differentncomposition. Alternatively, imprints or images of thenartificial or biological species can be obtained directly.nThe so formed preparations can be used in a vast varietynof appolications, e.g. as new drugs, inhibitors or newnaffinity materials. |