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filingDate 1998-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d8f18270bbf8f6d59aef14ed5c55f88
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publicationDate 2000-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0980368-A1
titleOfInvention 3-(pyrrolidin-3-yl)-1,3,4-oxadiazol-2(3h)-one derivatives and their use as 5-ht4 ligands
abstract The invention concerns compounds of general formula (I) in which R1 represents hydrogen or an alkyl or cycloalkylmethyl group, X1 represents hydrogen or a halogen or an alkoxy group or OR1 and X1 together represent a group of formula -OCH2O-, -O(CH2)2-, -O(CH2)3-, -O(CH2)2O, or -O(CH2)3O-, X2 represents hydrogen, an amino group or a group of general formula -NHCO2R in which R represents an alkyl or phenylalkyl group, X3 represents hydrogen or a halogen, and R2 represents hydrogen or an alkyl, phenylalkyl or [(4-dimethylamino)piperidin-1-ylcarbonyl]alkyl group. The invention is applicable in therapy. Said compounds can be used for treating or preventing disorders in which 5-HT4 receptors are involved, whether in the central nervous, the gastrointestinal, the cardiovascular or the urinary system.
priorityDate 1997-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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