http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0979079-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0264ab149dd139d522f7f14b1a3ea9e2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 1998-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e52fa114065f342ff60e970f382ddfbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_327cc4da8cd06c5a1b228eb75c5809a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4effec81aa97728a3fabb74ce1d9202 |
| publicationDate | 2000-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0979079-A1 |
| titleOfInvention | Use of tetrahydropyridine derivatives to prepare medicines for treating diseases causing demyelination |
| abstract | The invention concerns the use of tetrahydropyridine derivatives of formula (I) in which: R1 represents a halogen or a CF3, (C1-C4) alkyl or (C1-C4)alkoxy group; Y represents a nitrogen atom or a CH group; Z' and Z" represent each hydrogen or a (C1-C3) alkyl group, or one represents hydrogen and the other a hydroxy group, or both together represent an oxo group; Z represents a phenyl radical; a phenyl radical monosubstituted by a substituent X, X being (a) a (C1-C6)alkyl, (C1-C6)alkoxy (C3-C7)carboxyalkyl, (C1-C4)alkoxycarbonyl(C1-C6)alkyl, (C3-C7)carboxyalkoxy or (C1-C4)-alkoxycarbonyl(C1-C6) alkoxy group; (b) a group selected among a (C3-C7)cycloalkyl, (C3-C7)cycloalkoxy, (C3-C7)cycloalkylmethyl, (C3-C7)cycloalkylamino and cyclohexenyl group, said group capable of being substituted by a halogen, hydroxy, (C1-C4)alkoxy, carboxy, (C1-C4)alkoxycarbonyl, amino, mono- or di-(C1-C4)alkylamino; or (c) a group selected among a phenyl, phenoxy, phenylamino, N-(C1-C3)alkylphenylamino, phenylmethyl, phenylethyl, phenylcarbonyl, phenylthio, phenylsulphonyl, phenylsulphinyl or styryl group, said group can be mono- or polysubstituted on the phenyl group by a halogen, CF3, (C1-C4)alkyl, (C1-C4)alkoxy, cyano, amino, mono- or di-(C1-C4)alkylamino, (C1-C4)acylamino, carboxy, (C1-C4)alkoxycarbonyl, aminocarbonyl, mono- or di-(C1-C4)alkylaminocarbonyl, amino(C1-C4)alkyl hydroxy(C1-C4)alkyl or halogeno(C1-C4)alkyl; a phenyl radical disubstituted by a substituent R2, R2 being a halogen or a hydroxy, methyl, ethyl, (C3-C6)alkyl, (C1-C4)alkoxy or trifuoromethyl group and by a substituent X, X being as defined above; a 1-naphthyl or 2-naphthyl radical; a 1-naphthyl or 2-naphthyl radical, substituted in positions 5, 6, 7 and/or 8 by one or two hydroxyl groups, one or two (C1-C4) alkoxy groups, or a 6,7-methylenedioxy group; or Z" is hydrogen and Z and Z' represent, each independently, a phenyl group non-substituted or mono-, di- or trisubstituted; or one of its pharmaceutically acceptable salts or solvates, for preparing pharmaceutical compositions to fight against diseases causing demyelination. |
| priorityDate | 1997-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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