abstract |
The invention provides a process for the production of a compound of formula (I), which comprises reacting a compound of formula (II) with a compound of formula (III), in the presence of a strong base and a palladium(0) catalyst, at an elevated temperature, in a solvent which does not adversely affect the reaction. Compounds of formula (I) may be further processed to compounds of formula (V), which are useful in the treatment of inter alia migraine. |