abstract |
A colonic drug delivery composition contains anfirst polysaccharide and a second polysaccharidenwherein both polysaccharides are degradable by colonicnenzymes and are mixed at a environmental pH of about 7nor above. A colon selective pharmaceutical compositionnand dosage form for oral delivery of a drug, nutrient,ndiagnostic reagent, or mixture thereof includes thendrug, nutrient, diagnostic reagent, or mixture thereofnin contact with the polysaccharide composition. Anmethod of preparing such a colonic drug deliveryncomposition and the colon selective pharmaceuticalncomposition and dosage form are also disclosed. |