Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-36 |
filingDate |
1998-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97b9a5a54cdb98add3c96a918fb97809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0aaddd6c8e318f4579d67680d930fd0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0716d0b06d4afa8ab4a13398dfe85ab8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e84159df534da483e88462d97a979b8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c1ae756e1d9a981056a17882fc6e25a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8a493bd73c4a69ad7e96f98d69dd81a |
publicationDate |
2000-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0973527-A1 |
titleOfInvention |
Extended release formulations of erythromycin derivatives |
abstract |
Disclosed is a pharmaceutical composition for extended release of an erythromycin derivative in the gastrointestinal environment. The composition comprises an erythromycin derivative and a pharmaceutically acceptable polymer so that, when ingested orally, the composition induces statistically significantly lower Cmax in the plasma than an immediate release composition of the erythromycin derivative while maintaining bioavailability and minimum concentration substantially equivalent to that of the immediate release composition of the erythromycin derivative upon multiple dosing. The compositions of the invention have an improved taste profile and reduced gastrointestinal side effects as compared to those for the immediate release composition. |
priorityDate |
1997-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |