| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f21f475fb8289f608cd25f6010534ce |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-4046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-3869 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38 |
| filingDate |
1998-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a0a266ccd0a1ba579c9b00f78e97cf5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6ebaf312132f4463e2dd4e854359d6b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c6e3531c013694488dd5c880dcf400e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a224d03870786cf2dd443fa2814afaf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0791b2ef99c11d9aa983e9ffbd54a9ff |
| publicationDate |
2002-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0971939-B1 |
| titleOfInvention |
Bis-phosphonate conjugates with alkylating moieties having antitumor activity |
| abstract |
The present invention relates to conjugates of 3-carboxy-4,4'-dihydroxyphosphorylbutenoic acids with alkylating agents, derivatives are endowed with marked antitumor activity, especially against multiple myeloma. The present invention relates as well to a process for the preparation thereof and to pharmaceutical compositions containing them. |
| priorityDate |
1997-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |