| abstract |
New compounds, compositions and methods which find application in solidnphase synthesis including the preparation of high-density arrays of diverse polymernsequences such as diverse peptides and oligonucleotides as well as in preparation of arrays ofnsmall ligand molecules. The compounds of the present invention are those which arentypically referred to as linking groups, linkers or spacers and include unsymmetricalndisulfide linking groups, and 1,3-diol derivatives capable of providing a triggered release ofnan attached compound from a solid support under mild conditions. Additional newncompounds are labels which can be incorporated into either the 3' or 5' terminus of a DNAnoligomer. |