abstract |
The present invention relates to a percutaneous preparation comprisingnan adhesive layer formed on at least one side of a substrate, the layer containingnan acrylic copolymer, 6-amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)benzimidazolenor an acid addition salt thereof, and 2-mercaptobenzimidazole.nThis preparation exhibits superior percutaneousnabsorption of the benzimidazole compound and long sustention of efficacy, andnshows an improved stability of the active ingredient, benzimidazole compound, innthe preparation. |