Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_19ab225ef5940c4763c09703e9bd3ed6 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-091 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-655 |
filingDate |
1998-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2003-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_750232fb430e1c77da418172b70bea5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b06d7b11bb3b1e751336529b8eb197f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bfb60d6c3de5ca5a15b0d8f829a46c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87d9315899420a30af180aff57680156 |
publicationDate |
2003-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0965268-B1 |
titleOfInvention |
Thermostabilization, osmoprotection, and protection against desiccation of enzymes, cell components and cells by di-glycerol-phosphate |
abstract |
The utilization of di-glycerol-phosphate as a stabiliser of enzymes and other cell components or cells, namely against heat, freezing, desiccation, lyophilization or repeated usage, is disclosed. Examples with rubredoxin, lactate dehydrogenase and alcohol dehydrogenase show that this compound is a better protecting agent than glycerol. This solute is produced by organic chemical synthesis readily and efficiently in three steps from commercially available glycerol in its racemic forms. The optically pure forms can be synthesised in four steps from commercially available D-mannitol. Di-glycerol-phosphate is obtained in a highly pure state without the necessity of complicated and tedious purification procedures. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007097653-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007097653-A3 |
priorityDate |
1998-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |