Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33168c56094caae6de7b1a144448fe54 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10322 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10345 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-859 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 |
filingDate |
1999-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62856ef8199f84c67f0a2a43768fe3fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6a570da8cde95f98822ac5d20fc4a03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a87781d3e45d294b5a3cc118a59c9ec |
publicationDate |
1999-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0960942-A2 |
titleOfInvention |
Targeted delivery through a cationic amino acid transporter |
abstract |
The invention relates to the targeted delivery of substancesnto cells. The invention provides a virus-like particle orngene delivery vehicle provided with a ligand capable ofnbinding to a human amino acid transporter. Provided are fornexample ligands that can bind to the human transporter ofncationic L-amino acids (hCAT1). Such hCAT1 binding moleculesnfind applications in the design of vector systems for entryninto human or primate cells. Preferred are retroviralnenvelope molecules, which - when incorporated in a virusnparticle - can infect hCAT1 positive cells at highnfrequencies. Also within the scope of the invention arenmethods for the design of such hCAT1 binding molecules. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0040740-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6455314-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0102551-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0040740-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7419802-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7476517-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008100482-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008100482-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1016727-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0102551-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8088887-B2 |
priorityDate |
1998-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |