| abstract |
The invention concerns novel derivatives of 3,3-diphenylpropylamines, methods for theirnpreparation, pharmaceutical compositions containing the novel compounds, and the usenof the compounds for preparing drugs. More particularly the invention concerns tonprovide novel prodrugs of antimuscarinic agents with superior pharmacokinetic propertiesncompared to present drugs as oxybutynin and tolterodine, methods for preparing thereof,npharmaceutical compositions containing them, a method of using said compounds andncompositions for the treatment of urinary incontinence, gastrointestinal hyperactivityn(irritable bowel syndrome) and other smooth muscle contractile conditions. |