| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53dff29241864c5dc0eeca3fcbe40674 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1892 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 |
| filingDate |
1998-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e843d895a15c77e0cdca7fd28b4e3347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c700f5b4a849565a1c588533bc371b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0c142c90b4c3d2847d5d073abbc8903 |
| publicationDate |
1999-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0956284-A1 |
| titleOfInvention |
Process for selective derivatization of taxanes |
| abstract |
A process is described for converting the C(7) hydroxy group of a 10-acyloxy-7-hydroxytaxane to an acetal or ketal, the process comprising treating the 10-acyloxy-7-hydroxytaxane with a ketalizing agent in the presence of an acid catalyst to form a C(7) ketalized taxane of the formula or wherein either X<sup>31</sup> or X<sup>32</sup> represents the 10-acyloxy-7-hydroxytaxane moiety and the other of X<sup>31</sup> and X<sup>32</sup> as well as X<sup>33</sup> and X<sup>34</sup> are independently hydrocarbyl, substituted hydrocarbyl or heteroaryl moieties. Taxanes having a ketalized C(7) hydroxy group are also described. |
| priorityDate |
1997-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |