Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f91ed9eb2fdedee45742a75832da4c5b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6832 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6827 |
filingDate |
1997-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58bdd92c93b816f216b2784448911961 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4334044185ecec1894185c212337f9ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e9ca87e37adfeff7504a12d9746763c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67a2fec6d945e6f5dd77c07e5af54a5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c10ca4f8c2313b3edd36b53569a6ee0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccd17cd8b7b739cddf0f39c2d61eeb8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd942df5381c3e966e5a3c5103ac512b |
publicationDate |
1999-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0954610-A1 |
titleOfInvention |
Method for producing hybridisation complexes whose stability is substantially independent of the base composition of two hybridised nucleic acid molecules |
abstract |
The invention discloses a method for producing a hybridisation complex whose stability is substantially independent of the base composition of two hybridised nucleic acid molecules, consisting in contacting a first nucleic acid molecule with a second nucleic acid molecule under conditions enabling the formation of a specific hybridisation complex. The invention is characterised in that at least one of the four types of bases contained in the sequence of the first and/or of the second nucleic acid molecule is a modified base having pairing properties close to those of the natural base it replaces, such that at least one of the two types of the base pair contained in the composition of the complex comprises a modified base and in that the totality of the base pairs contained in the composition of the said complex has a like stability. |
priorityDate |
1996-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |